BDBM50049948 CHEMBL3317705

SMILES C[C@H]1NCCCN(c2ccc3ccccc3c2)C1=O

InChI Key InChIKey=WYRFRMLLNNWZHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049948   

TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049948(CHEMBL3317705)
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049948(CHEMBL3317705)
Affinity DataIC50: 570nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049948(CHEMBL3317705)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed