BDBM50049966 CHEMBL177948::[4-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-butyl]-phosphonic acid

SMILES Nc1nc2n(COCCCCP(O)(O)=O)cnc2c(=O)[nH]1

InChI Key InChIKey=LQGNKADADORFAP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049966   

TargetPurine nucleoside phosphorylase(Human)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50049966([4-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-b...)
Affinity DataKi:  56nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase isolated from human erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50049966([4-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-b...)
Affinity DataKi:  400nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed