BDBM50049986 (R)-2-{[2-{(S)-1-[(Azepane-1-carbonyl)-amino]-3-methyl-butyl}-5-(1-methyl-1H-indol-3-yl)-thiazole-4-carbonyl]-amino}-3-pyridin-2-yl-propionic acid::CHEMBL367176

SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)c1nc(C(=O)N[C@H](Cc2ccccn2)C(O)=O)c(s1)-c1cn(C)c2ccccc12

InChI Key InChIKey=HPKPZVJNKPHJON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049986   

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049986((R)-2-{[2-{(S)-1-[(Azepane-1-carbonyl)-amino]-3-me...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of Endothelin-1 binding to Endothelin A receptor binding sites in MMQ cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049986((R)-2-{[2-{(S)-1-[(Azepane-1-carbonyl)-amino]-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Endothelin-3 (ET-3) binding to Endothelin B receptor binding sites in porcine cerebellar membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed