BDBM50050479 3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15]heptadeca-10,12,14-trien-12-ol::CHEMBL60270

SMILES CN1CNC2CCC3(C)CC2(C1)Cc1ccc(O)cc31

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050479   

TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  17nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  27.7nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  863nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed