BDBM50050484 10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0*2,7*]trideca-2,4,6-trien-4-ol::CHEMBL409026

SMILES CC12CCC(N)C(CO)(Cc3ccc(O)cc13)C2

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50050484   

TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  40.6nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  41nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  109nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi: >1.00E+6nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed