BDBM50050485 (1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricyclo[7.4.1.0*2,7*]tetradeca-2(7),3,5-trien-4-ol::CHEMBL61644

SMILES COC[C@@]12Cc3ccc(O)cc3[C@@](C)(C1)CCCN2C

InChI Key InChIKey=QNQAGYMQGHYWCJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050485   

TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi:  102nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi:  795nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi: >5.00E+3nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed