BDBM50050576 1,3-Dimethyl-6-(2-propoxy-5-thiazol-2-yl-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one::CHEMBL295614

SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1nccs1

InChI Key InChIKey=WVNAOGQEBKSVSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50050576   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050576(1,3-Dimethyl-6-(2-propoxy-5-thiazol-2-yl-phenyl)-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed