BDBM50050847 CHEMBL3318027

SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1

InChI Key InChIKey=YZOZEZFNWLULHX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50050847   

TargetSerine/threonine-protein kinase pim-1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 260nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 429nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of c-Abl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50050847(CHEMBL3318027)
Affinity DataIC50: 7.95E+3nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed