BDBM50051296 7-Methoxy-2-phenyl-quinoline-4-carboxylic acid benzylamide::CHEMBL51120

SMILES COc1ccc2c(cc(nc2c1)-c1ccccc1)C(=O)NCc1ccccc1

InChI Key InChIKey=ULHFEESQDIXXBS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051296   

TargetNeuromedin-K receptor(Human)
Smithkline Beecham S.P.A. Milano

Curated by ChEMBL
LigandPNGBDBM50051296(7-Methoxy-2-phenyl-quinoline-4-carboxylic acid ben...)
Affinity DataKi:  870nMAssay Description:Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50051296(7-Methoxy-2-phenyl-quinoline-4-carboxylic acid ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against hTachykinin receptor 1 for the displacement of [3H]-substance P binding from Tachykinin receptor 1 CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Smithkline Beecham S.P.A. Milano

Curated by ChEMBL
LigandPNGBDBM50051296(7-Methoxy-2-phenyl-quinoline-4-carboxylic acid ben...)
Affinity DataKi:  5.33E+5nMAssay Description:Binding affinity against human Tachykinin receptor 3 for the displacement of [3H]-substance P binding from human Tachykinin receptor 3 CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed