BDBM50051406 2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{2-[((2S,6R)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-4-methyl-pentanoylamino}-propionylamino)-3-ethylsulfanyl-propionic acid::CHEMBL305524

SMILES CCSCC(NC(=O)[C@@H](Cc1c(Br)[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C(O)=O

InChI Key InChIKey=LZBDEPUGFFURHL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051406   

TargetEndothelin receptor type B(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051406(2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{2-[((2S,6R)-2,...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051406(2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{2-[((2S,6R)-2,...)
Affinity DataIC50: 1.90nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051406(2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{2-[((2S,6R)-2,...)
Affinity DataIC50: 3.60nMAssay Description:Binding affinity rowards Endothelin B receptor in human girardi heart cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051406(2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{2-[((2S,6R)-2,...)
Affinity DataIC50: 6.40nMAssay Description:Binding affinity towards Endothelin A receptor in human neuroblastoma-derived cell line SK-N-MC membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed