BDBM50052015 CHEMBL178011::Rutheium(II) triflate salt of (methyl (3S,5R)-8-methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylate)(penta methyl cyclo penta dinyl)::tri carbonyl methyl (3S,5R)-8-methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylate chromiumIII

SMILES COC(=O)C1C2CCC(CC1c1ccccc1)N2C

InChI Key

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50052015   

TargetSodium-dependent dopamine transporter(Human)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50052015(Rutheium(II) triflate salt of (methyl (3S,5R)-8-me...)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibitory activity against [3H]-Dopamine uptake from Dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50052015(Rutheium(II) triflate salt of (methyl (3S,5R)-8-me...)
Affinity DataIC50: 418nMAssay Description:Inhibitory activity against [3H]dopamine uptake from Dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50052015(Rutheium(II) triflate salt of (methyl (3S,5R)-8-me...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards dopamine transporter using [3H]WIN-35428 as radioligand from rat caudate putamen tissue (high affinity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50052015(Rutheium(II) triflate salt of (methyl (3S,5R)-8-me...)
Affinity DataKi:  124nMAssay Description:Binding affinity towards dopamine transporter using [3H]WIN-35428 as radioligand from rat caudate putamen tissue (low affinity for one set model)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50052015(Rutheium(II) triflate salt of (methyl (3S,5R)-8-me...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards dopamine transporter using [3H]WIN-35428 as radioligand from rat caudate putamen tissue (low affinity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50052015(Rutheium(II) triflate salt of (methyl (3S,5R)-8-me...)
Affinity DataKi:  2.28E+3nMAssay Description:Binding affinity towards dopamine transporter using [3H]WIN-35428 as radioligand from rat caudate putamen tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed