BDBM50052164 (2S,5R)-3-(4-Iodo-phenyl)-8-methyl-2-(3-phenyl-isoxazol-5-yl)-8-aza-bicyclo[3.2.1]octane::CHEMBL92072

SMILES CN1[C@@H]2CCC1[C@H](C(C2)c1ccc(I)cc1)c1cc(no1)-c1ccccc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50052164   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50052164((2S,5R)-3-(4-Iodo-phenyl)-8-methyl-2-(3-phenyl-iso...)
Affinity DataIC50: 2.60nMAssay Description:Binding affinity against Dopamine transporter using [3H]WIN-35 428 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50052164((2S,5R)-3-(4-Iodo-phenyl)-8-methyl-2-(3-phenyl-iso...)
Affinity DataIC50: 100nMAssay Description:Binding affinity against serotonin transporter using [3H]paroxetine in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50052164((2S,5R)-3-(4-Iodo-phenyl)-8-methyl-2-(3-phenyl-iso...)
Affinity DataIC50: 868nMAssay Description:Binding affinity against Norepinephrine transporter using [3H]nisoxetine in midbrain of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed