BDBM50052279 (2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-1-(1H-tetrazol-5-ylmethyl)-piperidine::CHEMBL327736

SMILES FC(F)(F)c1cc(CO[C@H]2CCCN(Cc3nnn[nH]3)[C@H]2c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=LFFPDSZQTVWQEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052279   

TargetSubstance-P receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50052279((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50: 39.8nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50052279((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50: 43nMAssay Description:Displacement of [125 I]-Tyr8 SP from the cloned human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed