BDBM50052596 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid methyl ester::CHEMBL88935

SMILES COC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc(OC)c(OC)c1

InChI Key InChIKey=GHTLZEXBRLQMFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052596   

LigandPNGBDBM50052596(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052596(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed