BDBM50052598 CHEMBL109264::N-Benzyl-3-(3,4-dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide

SMILES COc1ccc(cc1OC)C(CC(=O)NCc1ccccc1)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=JWEDWYXWMXOFMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052598   

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052598(N-Benzyl-3-(3,4-dimethoxy-phenyl)-3-(1,3-dioxo-1,3...)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed