BDBM50052599 3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL89890

SMILES COc1ccc(cc1OC)C(CC(N)=O)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=GKPXSGPDRIUIAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052599   

LigandPNGBDBM50052599(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of PDE4 enzyme from U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052599(3-(3,4-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed