BDBM50052602 3-(4-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester::CHEMBL110421

SMILES COC(=O)CC(N1C(=O)c2cccc(N)c2C1=O)c1ccc(OC)c(OC)c1

InChI Key InChIKey=UHHZKWNCNDFRNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052602   

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052602(3-(4-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-...)
Affinity DataIC50: 450nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed