BDBM50052604 3-(3,4-Dimethoxy-phenyl)-3-(4-nitro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid methyl ester::CHEMBL327083

SMILES COC(=O)CC(N1C(=O)c2cccc(c2C1=O)[N+]([O-])=O)c1ccc(OC)c(OC)c1

InChI Key InChIKey=CTNMKDMXDXFPNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052604   

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052604(3-(3,4-Dimethoxy-phenyl)-3-(4-nitro-1,3-dioxo-1,3-...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibitory activity of TNF-alpha was measured in the supernatant of human PBMCs stimulated with LPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed