BDBM50052614 3-(4-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL110972

SMILES NC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccc(cc1)C#N

InChI Key InChIKey=VPJCFBWLVYCZOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052614   

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052614(3-(4-Cyano-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoind...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed