BDBM50052673 Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-ethyl ester::CHEMBL112509

SMILES C[C@H](OC(=O)C12CC3CC(CC(C3)C1)C2)c1cccnc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50052673   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50: 230nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50: 840nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed