BDBM50052809 CHEMBL3318728

SMILES C[C@@H](Oc1ccccc1)c1cc(cn2c1nc(cc2=O)N1CCOCC1)C(=O)N(C)CCO

InChI Key InChIKey=IEYLWEAQUDHMKS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052809   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052809(CHEMBL3318728)Copy SMILESCopy InChI

Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human recombinant PI3Kgamma assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052809(CHEMBL3318728)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL