BDBM50052814 CHEMBL3318705

SMILES CC(Nc1cc(Cl)ccc1C(O)=O)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1

InChI Key InChIKey=IPFXWGVWKQFAMJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052814   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052814(CHEMBL3318705)Copy SMILESCopy InChI

Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052814(CHEMBL3318705)Copy SMILESCopy InChI

Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL