BDBM50052818 CHEMBL3318725

SMILES COc1cccc(OC(C)c2cc(cn3c2nc(cc3=O)N2CCOCC2)C(=O)N(C)CCO)c1

InChI Key InChIKey=LRVAMSBEZQHIFB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052818   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052818(CHEMBL3318725)Copy SMILESCopy InChI

Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052818(CHEMBL3318725)Copy SMILESCopy InChI

Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL