BDBM50052820 CHEMBL3318723

SMILES CC(Oc1cccc(c1)C#N)c1cc(cn2c1nc(cc2=O)N1CCOCC1)C(=O)N(C)CCO

InChI Key InChIKey=VDOVOAZEAKWMTD-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052820   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052820(CHEMBL3318723)Copy SMILESCopy InChI

Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50052820(CHEMBL3318723)Copy SMILESCopy InChI

Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL