BDBM50053457 1-(6-Bromo-pyridin-2-yl)-[1,2,4]triazinan-3-one::CHEMBL340784

SMILES Brc1cccc(n1)N1CCNC(=O)N1

InChI Key InChIKey=GRQXIWVBEWUYTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053457   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053457(1-(6-Bromo-pyridin-2-yl)-[1,2,4]triazinan-3-one | ...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50053457(1-(6-Bromo-pyridin-2-yl)-[1,2,4]triazinan-3-one | ...)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed