BDBM50053702 3-(4-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperazin-1-yl}-butyl)-1-thia-3-aza-spiro[4.5]decan-4-one::CHEMBL131159

SMILES Fc1ccc(cc1)-n1cc(N2CCN(CCCCN3CSC4(CCCCC4)C3=O)CC2)c2ccccc12

InChI Key InChIKey=CSGPIHKZIYRGPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053702   

TargetD(2) dopamine receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50053702(3-(4-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-pipera...)
Affinity DataIC50: 18nMAssay Description:Binding affinity towards Dopamine receptor D2 was determined in rat striatum using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50053702(3-(4-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-pipera...)
Affinity DataIC50: 9.03E+3nMAssay Description:Binding affinity towards serotonin 5-HT1A receptor was determined in rat hippocampus using [3H]8-OH-DPAT as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed