BDBM50053722 3-{4-[4-(2,3-Dimethyl-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL132825

SMILES Cc1cccc(N2CCN(CCCCN3CSCC3=O)CC2)c1C

InChI Key InChIKey=NDHQLVTVKGJPKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053722   

Target5-hydroxytryptamine receptor 1A(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50053722(3-{4-[4-(2,3-Dimethyl-phenyl)-piperazin-1-yl]-buty...)
Affinity DataIC50: 83nMAssay Description:Binding affinity towards serotonin 5-HT1A receptor was determined in rat hippocampus using [3H]8-OH-DPAT as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50053722(3-{4-[4-(2,3-Dimethyl-phenyl)-piperazin-1-yl]-buty...)
Affinity DataIC50: 778nMAssay Description:Binding affinity towards Dopamine receptor D2 was determined in rat striatum using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed