BDBM50053757 5-[1-Pyrimidin-5-yl-1-(3-trifluoromethyl-phenyl)-meth-(E)-ylideneaminooxy]-pentanoic acid::CHEMBL129843

SMILES OC(=O)CCCCO\N=C(/c1cccc(c1)C(F)(F)F)c1cncnc1

InChI Key InChIKey=GSKDOLRDUIVNHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053757   

TargetThromboxane-A synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50053757(5-[1-Pyrimidin-5-yl-1-(3-trifluoromethyl-phenyl)-m...)
Affinity DataIC50: 39nMAssay Description:TXA2 synthetase inhibition measured by the inhibition of TXB2 formation by human gel-filtered platelets incubated with [14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50053757(5-[1-Pyrimidin-5-yl-1-(3-trifluoromethyl-phenyl)-m...)
Affinity DataIC50: 1.50E+3nMAssay Description:TXA2 receptor antagonism, measured by the displacement of [3H]SQ29,548 from the PGH-2/TXA-2 receptor on human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed