BDBM50054128 2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3,4-b]quinolin-(3E)-ylidene]-N,N-dipropyl-acetamide::CHEMBL134590

SMILES CCCN(CCC)C(=O)\C=C1\N(C(=O)c2cc3ccccc3nc12)c1ccc(Cl)cc1

InChI Key InChIKey=NXVPVFGSKVBDIO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50054128   

TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]PK11195 from rat kidney peripheral benzodiazepine receptor (type 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 4.90nMAssay Description:Displacement of [3H]PK11195 from rat cerebral cortex peripheral benzodiazepine receptor (type 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex membrane incubated for 120 mins by liquid scintillation spectrometer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 40nMAssay Description:Binding affinity against peripheral benzodiazepine receptor( PBR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 40nMAssay Description:Binding affinity against peripheral benzodiazepine receptor( PBR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]Ro-5-4864 from rat cerebral cortex peripheral benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]PK11195 from rat kidney peripheral benzodiazepine receptor (type 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054128(2-[2-(4-Chloro-phenyl)-1-oxo-1,2-dihydro-pyrrolo[3...)
Affinity DataIC50: 210nMAssay Description:Displacement of [3H]PK11195 from rat cerebral cortex peripheral benzodiazepine receptor (type 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed