BDBM50054342 8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL138998

SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@@H]1CCc2c(F)cccc2C1

InChI Key InChIKey=BYVRVQNZFICZEB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054342   

Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054342(8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  0.246nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054342(8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]raclopride from Dopamine receptor D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054342(8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  4.94nMAssay Description:Displacement of [3H]quinpirole from Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054342(8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  17nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed