BDBM50054490 CHEMBL138243::N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-[(S)-2-oxo-3-(2-phenyl-ethanesulfonylamino)-piperidin-1-yl]-acetamide

SMILES NC(=N)C1CCC[C@H](NC(=O)CN2CCC[C@H](NS(=O)(=O)CCc3ccccc3)C2=O)C1O

InChI Key InChIKey=KSPYJLUHOLRXAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054490   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054490(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-[(S...)
Affinity DataIC50: 420nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054490(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-[(S...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054490(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-[(S...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed