BDBM50054573 (Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoromethylsulfanyl-phenyl)-acrylamide::CHEMBL141248

SMILES FC(F)(F)Sc1ccc(NC(=O)C(C#N)C(=O)C2CC2)cc1

InChI Key InChIKey=NYPCOHOWTLQKKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054573   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054573((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054573((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed