BDBM50055574 CHEMBL3321798

SMILES [H][C@]12CCCC[C@]1([H])CN(CC\C=C\CCN1C(=O)Cc3ccccc13)CC2

InChI Key InChIKey=STLOWRIFEMHPHS-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50055574   

Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed