BDBM50055653 10-[[[1-(Methoxymethyl)-2-[[3-(dimethylamino)propyl]carbamoyl]pyrrol-4-yl]carbamoyl]methoxy]-2(R,S)-camptothecin::CHEMBL312690

SMILES CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(OCC(=O)ONc5cc(C(=O)NCCCN(C)C)n(COC)c5)cc4cc3Cn1c2=O

InChI Key InChIKey=OUCJUOXGHQDEQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055653   

TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055653(10-[[[1-(Methoxymethyl)-2-[[3-(dimethylamino)propy...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed