BDBM50055661 4-(4-Dimethylamino-butyrylamino)-1-methoxymethyl-1H-pyrrole-2-carboxylic acid [2-(4-ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-9-yloxy)-ethyl]-amide::CHEMBL72828

SMILES CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(OCCNC(=O)c5cc(NC(=O)CCCN(C)C)cn5COC)cc4cc3Cn1c2=O

InChI Key InChIKey=ZSMCYFPCVZXTLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055661   

TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055661(4-(4-Dimethylamino-butyrylamino)-1-methoxymethyl-1...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed