BDBM50055871 4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piperidine::CHEMBL33903

SMILES Brc1ccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1

InChI Key InChIKey=PRQJTMVANYBIPV-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50055871   

LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataIC50: 1.49E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataIC50: 31.1nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [3H]dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataKi:  6.40nMAssay Description:Affinity at rat dopamine transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataKi:  534nMAssay Description:Inhibition of [3H]norepinephrine uptake at the rat norepinephrine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataKi:  988nMAssay Description:Affinity at rat serotonin transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataKi:  1.32E+3nMAssay Description:Inhibition of [3H]5-HT uptake at the rat serotonin transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed