BDBM50056228 6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL423558

SMILES COc1cc(CCC2CNc3nc(N)nc(N)c3C2)cc(OC)c1OC

InChI Key InChIKey=LSTAJDZVPLRJIW-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50056228   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 470nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Toxoplasma gondii (tg)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Rat liver (rl)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Pneumocystis carinii (pc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056228(6-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed