BDBM50056232 CHEMBL342555::N-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-N-(3,4,5-trimethoxy-phenyl)-formamide

SMILES COc1cc(cc(OC)c1OC)N(Cc1cnc2nc(N)nc(N)c2c1)C=O

InChI Key InChIKey=CEQFUVIGWFFFGQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50056232   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056232(N-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056232(N-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Toxoplasma gondii (tg)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056232(N-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Rat liver (rl)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056232(N-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056232(N-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056232(N-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Pneumocystis carinii (pc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed