BDBM50056246 6-[(2,5-Dimethoxy-4-pyrrol-1-yl-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL435479

SMILES COc1cc(c(OC)cc1NCc1cnc2nc(N)nc(N)c2c1C)-n1cccc1

InChI Key InChIKey=MEMOEPDTNVWCFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056246   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056246(6-[(2,5-Dimethoxy-4-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056246(6-[(2,5-Dimethoxy-4-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056246(6-[(2,5-Dimethoxy-4-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed