BDBM50056584 (S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-2,5-dioxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-butyric acid::CHEMBL163620

SMILES C[C@@H](CC(O)=O)N1CC(=O)N(C)c2ccc(cc2C1=O)C#Cc1ccc(cc1)C(N)=N

InChI Key InChIKey=WUDMWSRCKXOKCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056584   

TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056584((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 5nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056584((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056584((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 138nMAssay Description:Inhibition of thrombin-induced platelet aggregation assay at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed