BDBM50056589 (S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethynyl)-2,5-dioxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-butyric acid::CHEMBL163365

SMILES C[C@@H](CC(O)=O)N1CC(=O)N(c2ccc(cc2C1=O)C#Cc1ccc(cc1)C(N)=N)C(C)(C)C

InChI Key InChIKey=BXPUXQXIESIGAE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056589   

TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056589((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 3nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plate; 3:1 mixture enriched in the faster eluting diastereoisomerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056589((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 12nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plate; 1:3 mixture enriched in the slower eluting diastereoisomerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056589((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 92nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed