BDBM50056697 CHEMBL3326925

SMILES CCCCCn1c(N)nc2c1ccc1ccccc21

InChI Key InChIKey=QCTFAPBPHMREKD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056697   

TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50056697(CHEMBL3326925)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50056697(CHEMBL3326925)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed