BDBM50057033 CHEMBL3326129

SMILES COc1ccc(OC)c(Sc2ccc3nnc(-c4cn(C)nc4C)n3n2)c1

InChI Key InChIKey=QLCNPAADINOYLN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057033   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50057033(CHEMBL3326129)Copy SMILESCopy InChI

Affinity DataIC50: 323nMAssay Description:Inhibition of GST-tagged truncated LRRK2 (unknown origin) using fluorescein-labeled peptide LRRKtide as substrate by LANTHA screen assay in presence ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50057033(CHEMBL3326129)Copy SMILESCopy InChI

Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of phosphorylation at S935 residue of wild-type full-length LRRK2 kinase (unknown origin) expressed in HEK 293 cells after 90 mins by ELIS...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL