BDBM50057035 CHEMBL3326127

SMILES COc1ccc(OC)c(Sc2ccc3nnc(-c4ccn(C)n4)n3n2)c1

InChI Key InChIKey=KKRQBSOWBUDWFB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057035   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50057035(CHEMBL3326127)Copy SMILESCopy InChI

Affinity DataIC50: 224nMAssay Description:Inhibition of GST-tagged truncated LRRK2 (unknown origin) using fluorescein-labeled peptide LRRKtide as substrate by LANTHA screen assay in presence ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
Copy BDB DOIPubMed
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50057035(CHEMBL3326127)Copy SMILESCopy InChI

Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of phosphorylation at S935 residue of wild-type full-length LRRK2 kinase (unknown origin) expressed in HEK 293 cells after 90 mins by ELIS...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL