BDBM50057292 (5aS,7aS,10aS,10bS)-7a-Methyl-3,4,5a,6,7,7a,9,10,10a,10b,11,12-dodecahydro-indeno[4,5-c]quinolizine-2,8-dione::CHEMBL274238

SMILES C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CCN34)[C@@H]1CCC2=O

InChI Key InChIKey=ABCDBBYVLBHVSH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057292   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50057292((5aS,7aS,10aS,10bS)-7a-Methyl-3,4,5a,6,7,7a,9,10,1...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition against 5 alpha R-2 in human prostate homogenate relative to finasterideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50057292((5aS,7aS,10aS,10bS)-7a-Methyl-3,4,5a,6,7,7a,9,10,1...)
Affinity DataIC50: 299nMAssay Description:Inhibitory activity against human 5-alpha Reductase-1 expressed in DU-145 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50057292((5aS,7aS,10aS,10bS)-7a-Methyl-3,4,5a,6,7,7a,9,10,1...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against 5-alpha Reductase-2 on human prostate homogenates from surgically derived benign hyperplastic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed