BDBM50057312 5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL278261

SMILES CN(Cc1c[nH]c2nc(N)nc(N)c12)c1cccc2ccccc12

InChI Key InChIKey=VGMMWZWEERBTOC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057312   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 870nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 870nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed