BDBM50057314 2-({4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-ylmethyl)-methyl-amino]-benzoyl}-methyl-amino)-pentanedioic acid::CHEMBL17287

SMILES CN(Cc1c[nH]c2nc(N)nc(N)c12)c1ccc(cc1)C(=O)N(C)C(CCC(O)=O)C(O)=O

InChI Key InChIKey=FZLSWQFQXKTWEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057314   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057314(2-({4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-y...)
Affinity DataIC50: 44nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057314(2-({4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-y...)
Affinity DataIC50: 60nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057314(2-({4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-y...)
Affinity DataIC50: 150nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed