BDBM50057436 CHEMBL25213::[2-(6-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine

SMILES COc1ccc(CCCCNCCOc2cc(F)cc3CCCOc23)cc1

InChI Key InChIKey=ZRVOLZXRGXGYEH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057436   

Target5-hydroxytryptamine receptor 1A(Rat)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057436([2-(6-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057436([2-(6-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy...)
Affinity DataKi:  0.221nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor on rat hippocampus using [3H]8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057436([2-(6-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy...)
Affinity DataKi:  0.259nMAssay Description:Binding affinity against dopamine receptor D2 on rat striatum using [3H]spiperone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057436([2-(6-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy...)
Affinity DataKi:  0.260nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed