BDBM50057566 4-(4-Chloro-5-phenyl-pyrazol-1-yl)-benzenesulfonamide::CHEMBL282301

SMILES NS(=O)(=O)c1ccc(cc1)-n1ncc(Cl)c1-c1ccccc1

InChI Key InChIKey=AJYWXMJXJSEWLW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057566   

TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057566(4-(4-Chloro-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50: 49.0nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057566(4-(4-Chloro-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057566(4-(4-Chloro-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50: 49nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057566(4-(4-Chloro-5-phenyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50: 3.10E+4nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed