BDBM50057936 2-(4-Chloro-phenyl)-4-methanesulfonylmethyl-1-(4-methanesulfonyl-phenyl)-1H-imidazole::CHEMBL43217

SMILES CS(=O)(=O)Cc1cn(c(n1)-c1ccc(Cl)cc1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=WDTNCQLTFLMBIG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057936   

TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057936(2-(4-Chloro-phenyl)-4-methanesulfonylmethyl-1-(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057936(2-(4-Chloro-phenyl)-4-methanesulfonylmethyl-1-(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057936(2-(4-Chloro-phenyl)-4-methanesulfonylmethyl-1-(4-m...)
Affinity DataIC50: 9.99E+6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed